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Realifessence is the region's leading provider of comprehensive healthcare services and the largest recruiter in alternative health. We believe that the quality of our services relies upon the quality of the individuals who make up our organizations and provide those services. In return, we provide outstanding career opportunities with competitive incentives and benefits packages. Realifessence seeks professional, caring persons to support our commitment to providing exceptional healthcare services to our community and you can join our award-winning team.

With today’s farming methods depleting the natural mineral content of our lands, we can no longer rely on our foods to completely provide us with the essential vitamins and minerals that our bodies need. We source for nutritional products are made from the finest ingredients, grown from the best sources and produced with the most advanced technology. Each product retains its original nutritional value, encouraging both good health and peace of mind. Because we only want the best for our highly esteemed customers, we provide only the best. Good health starts with good nutrition. 

In addition, several independent organizations that offer quality testing and allow products that pass these tests to display their seals of approval have approved of all the products recommended here in. These seals of approval provide assurance that the product was properly manufactured, contains the ingredients listed on the label, and does not contain harmful levels of contaminants. 

“For the first time in the history of the world every human being is now subjected to contact with dangerous chemicals, from the moment of conception until death.” …..Rachel Carson

Modern living exposes all of us to an unprecedented number of chemicals on a daily basis. This includes environmental toxins such as heavy metals, pesticides, industrial compounds and chemical byproducts, medications, cosmetic additives, inorganic chemicals, etc. These chemical substances which are foreign to the biological system are referred to as “xenobiotics.”

The good news is that the body was designed to detoxify and excrete xenobiotics. The bad news is our bodies may not always be equipped to handle the volume of modern, environmental pollutants and toxic substances. This problem may be exacerbated by the fact that the refining of many of our foodstuffs has caused them to provide considerably less of the nutrients that are essential to the detoxification process.1-2

The ramifications of toxic overload can vary from one individual to another. One possible ramification is multiple chemical sensitivities (MCS). MCS is a condition in which a person experiences various symptoms in response to being exposed to certain types of chemicals, primarily (but not limited to) those of petroleum and coal-tar derivation. The possible symptoms are many and may include headaches, fatigue, depression and an overall feeling of malaise and being sick.

MCS seems to develop after consistent, long-term exposure to certain chemicals at home or in the workplace. Eventually, the person develops intolerance to these chemicals, and starts suffering from MCS. For many MCS people, a sensitivity reaction will occur when exposed to even minute amounts of the offending chemicals which, in turn, can lead to severe symptoms characteristic of the MCS condition.3Of course an individual may suffer from toxic overload without having full-blown MCS. In fact, the most common symptom of toxic overload is probably fatigue. Other common symptoms include headache, muscle and joint pain, irritability, depression, mental confusion, gastrointestinal and/or cardiovascular irregularities, flu-like symptoms or allergic reactions including hives, stuffy or runny nose, sneezing and coughing.

Furthermore, some researchers have suggested that toxic overload may contribute to autoimmune diseases including inflammatory and rheumatoid arthritis, and neurological diseases such as Alzheimer’s and Parkinson’s.

HELP YOUR LIVER TO BECOME MORE PROFICIENT AT DETOXIFICATION.

So now let’s have a brief overview on how the liver goes about detoxification.

Water soluble toxins can pass through our bodies unchanged and be eliminated in the stool, sweat or urine. Fat soluble toxins, however, cannot be excreted without undergoing metabolic transformation (detoxification) in the liver so that they can become water soluble. Liver cells have sophisticated mechanisms to break down toxic substances. These include both endogenous (produced by the body) and exogenous (obtained from the environment; i.e., xenobiotics) substances. Every drug, chemical, pesticide and hormone, is broken down or metabolized via detoxification pathways in the liver called “phase 1” and “phase 2.”

 

PHASE 1

Phase 1 utilizes cytochrome P450 enzymes produced in the liver. These enzymes initiate reactions that generally involve exposing or adding a “functional group” to the toxic molecule. This process of making the molecule more reactive is required as the first step in increasing its water solubility for excretion. Some chemicals are already highly reactive and they have functional groups, so they can bypass phase 1 and go right to “phase 2”. The majority, however, first need “phase 1” activation.

Unfortunately, phase 1 does generate free radicals which mean that there is greater potential for oxidative damage at this time.

PHASE 2

Phase 2 involves the coupling (attaching) or conjugation of a water soluble substance which is endogenously produced or sourced by the body, to the toxin. This makes the toxic molecule more water soluble and therefore less toxic. If the molecule is large, it is then excreted via the bile. Otherwise, it is excreted in the urine.

Now that we’ve briefly examined the process of liver detoxification, let’s take a look at how we can use dietary supplements to support and promote liver detoxification.

Amino acids and trimethylglycine

Certain amino acids are used in phase 2 as the water soluble substance that is conjugated (attached) to the toxic molecule. These amino acids include glycine, taurine, and glutamine. Clinically, supplementation with these amino acids has shown great benefit for patients with toxic overload, especially when body cleansing was undertaken contemporaneously.18Likewise, methyl groups also act as conjugating agents in phase 2. Trimethylglycine (betaine) is a donor of methyl groups, and may be useful as such in biochemical reactions in the liver.

Garlic appears to induce both phase 1 and phase 2 enzymes. In addition, aged garlic extract may increase the glutathione level and glutathione related enzymes which aid in detoxifying the body. Research has also suggested that garlic extract may help to protect the body from heavy metal poisoning. When garlic extract was combined with red blood cells it prevented lead, mercury and aluminum from destroying them. Without the garlic extract, these heavy metals ruptured the red blood cells.